Welcome to PhosphoGRID

PhosphoGRID is an online database of experimentally verified in vivo protein phosphorylation sites in the model eukaryotic organism Saccharomyces cerevisisae. The database includes results from both high throughput (HTP) MS proteomics studies in addition to phosphosites identified in low throughput (LTP) studies of individual proteins or protein complexes. The identity of specific protein kinases and phosphatases shown to regulate appearance of phosphorylations are recorded, where available, as are the function(s) of the phosphorylation, and conditions under which the modification was demonstrated to occur. The PhosphoGRID curators would appreciate comments on omissions and errors, as well as notifications of newly published or submitted data.

This work was supported by:

  • Canadian Institutes of Health Research grant (MOP-77807 - to I.S.)
  • Canadian Cancer Society Research Institute Grant (0011258 to I.S.)
  • Canadian Institutes of Health Research grant (GSP-36651 to M.T.)
  • NIH National Center for Research Resources Grant (1R01RR024031-01 to M.T. and K.D.)


Latest News

BioGRID Version 3.4.138 Released

July 1, 2016 - 1:13 am

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 56,795 publications. These additions bring our total number of non-redundant interactions to 833,833, raw interactions to 1,068,567, non-redundant chemical associations to 11,694, raw chemical associations to 27,501, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

BioGRID Version 3.4.137 Released

June 1, 2016 - 5:18 am

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 56,683 publications. These additions bring our total number of non-redundant interactions to 832,938, raw interactions to 1,067,443, non-redundant chemical associations to 11,694, raw chemical associations to 27,501, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

BioGRID Version 3.4.136 Released

May 1, 2016 - 2:25 am

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 56,621 publications. These additions bring our total number of non-redundant interactions to 832,222, raw interactions to 1,066,335, non-redundant chemical associations to 11,694, raw chemical associations to 27,501, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

BioGRID Version 3.4.135 Released

April 1, 2016 - 4:25 am

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 56,600 publications. These additions bring our total number of non-redundant interactions to 827,858, raw interactions to 1,060,041, non-redundant chemical associations to 11,694, raw chemical associations to 27,501, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

BioGRID Version 3.4.134 Released

March 1, 2016 - 5:21 am

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 55,957 publications. These additions bring our total number of non-redundant interactions to 824,302, raw interactions to 1,055,196, non-redundant chemical associations to 11,694, raw chemical associations to 27,501, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

BioGRID Version 3.4.133 Release Tops One Million Interactions

January 30, 2016 - 3:19 am

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 55,699 publications. These additions bring our total number of non-redundant interactions to 822,766, raw interactions to 1,052,258, non-redundant chemical associations to 11,694, raw chemical associations to 27,501, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

Two New Protocol Papers Demonstrate BioGRID Usage in Yeast

January 5, 2016 - 6:43 pm

Newly released BioGRID protocol papers demonstrate techniques in which our data are utilized as a resource for the study of biological interaction data in yeast. The following publications are available now:

Use of the BioGRID Database for Analysis of Yeast Protein and Genetic Interactions
Oughtred R et. al.
Cold Spring Harb Protoc. 2016

BioGRID: A Resource for Studying Biological Interactions in Yeast.
Oughtred R et al.
Cold Spring Harb Protoc. 2016

BioGRID Version 3.4.132 Released

January 1, 2016 - 3:19 am

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 55,519 publications. These additions bring our total number of non-redundant interactions to 757,476, raw interactions to 980,467, non-redundant chemical associations to 11,694, raw chemical associations to 27,501, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

BioGRID Version 3.4.131 Released

December 1, 2015 - 6:19 am

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 55,346 publications. These additions bring our total number of non-redundant interactions to 749,213, raw interactions to 971,115, non-redundant chemical associations to 11,329, raw chemical associations to 27,034, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

BioGRID Version 3.4.130 Released

November 1, 2015 - 4:18 am

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 55,326 publications. These additions bring our total number of non-redundant interactions to 749,199, raw interactions to 971,027, non-redundant chemical associations to 11,329, raw chemical associations to 27,034, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

National Institutes of HealthBiotechnology and Biological Sciences Research CouncilCanadian Institutes of Health ResearchThe University of EdinburghPrinceton UniversitySamuel Lunenfeld Research InstituteSaccharomyces Genome DatabaseFlybaseGeneDBNational Center for Biotechnology InformationHuman Protein Reference DatabaseWormbaseGene OntologyThe International Molecular Exchange ConsortiumDatabase of Interacting ProteinsIntACTMolecular Interaction DatabaseProteomics Standards InitiativeReactomeCytoscapeOsprey Network Visualization SystemPathway Commons