Welcome to PhosphoGRID

PhosphoGRID is an online database of experimentally verified in vivo protein phosphorylation sites in the model eukaryotic organism Saccharomyces cerevisisae. The database includes results from both high throughput (HTP) MS proteomics studies in addition to phosphosites identified in low throughput (LTP) studies of individual proteins or protein complexes. The identity of specific protein kinases and phosphatases shown to regulate appearance of phosphorylations are recorded, where available, as are the function(s) of the phosphorylation, and conditions under which the modification was demonstrated to occur. The PhosphoGRID curators would appreciate comments on omissions and errors, as well as notifications of newly published or submitted data.

This work was supported by:

  • Canadian Institutes of Health Research grant (MOP-77807 - to I.S.)
  • Canadian Cancer Society Research Institute Grant (0011258 to I.S.)
  • Canadian Institutes of Health Research grant (GSP-36651 to M.T.)
  • NIH National Center for Research Resources Grant (1R01RR024031-01 to M.T. and K.D.)


NOTICE OF REDIRECTION

PhosphoGRID search results have been permanently re-directed into the BioGRID website as our scope has expanded to cover additional post translational modifications and additional model organisms. These and ALL future efforts of our ongoing curation of post translational modifications are available online now at the BioGRID Website.



Latest News

Comprehensive Update to Fruit Fly Dataset from FlyBase includes 8,000+ New Interactions

December 1, 2018 - 1:43 pm

BioGRID update 3.5.167 includes a comprehensive update to our Drosophila melanogaster (Fruit Fly) dataset in ongoing partnership with FlyBase.org. This update verifies and validates more than 68,000 existing interactions and incorporates an additional 8,000+ new interactions across more than 6,100 total publications. This update also increases the total number of Drosophila melanogaster interactions deposited in BioGRID to 76,657. These interactions and all associated meta data are available immediately online via all standard BioGRID searches and supported download formats. You can also find them available at FlyBase.org in all search result pages.

A special thanks to the entire FlyBase Consortium for their tireless curation efforts and in particular Julie Agapite and Gil dos Santos for directly helping to facilitate the BioGRID collaboration.

If you have an interaction dataset you'd like to deposit directly into the BioGRID, please contact us at biogridadmin@gmail.com.

BioGRID Version 3.5.167 Released

December 1, 2018 - 3:13 am

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 67,763 publications. These additions bring our total number of non-redundant interactions to 1,279,126, raw interactions to 1,650,607, non-redundant chemical associations to 12,015, raw chemical associations to 28,093, Non-Redundant PTM Sites to 367,288, Raw PTM Sites to 668,982 and Un-Assigned PTMs to 57,396. New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

BioGRID Version 3.5.166 Released

November 1, 2018 - 5:12 am

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 67,477 publications. These additions bring our total number of non-redundant interactions to 1,255,578, raw interactions to 1,623,645, non-redundant chemical associations to 12,015, raw chemical associations to 28,093, Non-Redundant PTM Sites to 367,288, Raw PTM Sites to 668,982 and Un-Assigned PTMs to 57,396. New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

BioGRID Version 3.5.165 Released

September 26, 2018 - 9:41 am

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 66,164 publications. These additions bring our total number of non-redundant interactions to 1,243,659, raw interactions to 1,607,037, non-redundant chemical associations to 12,015, raw chemical associations to 28,093, Non-Redundant PTM Sites to 367,288, Raw PTM Sites to 668,982 and Un-Assigned PTMs to 57,396. New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

BioGRID Version 3.4.164 Released

September 1, 2018 - 3:22 am

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 65,816 publications. These additions bring our total number of non-redundant interactions to 1,238,062, raw interactions to 1,598,688, non-redundant chemical associations to 11,820, raw chemical associations to 27,785, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 19,047. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

BioGRID Version 3.4.163 Released

August 1, 2018 - 2:05 am

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 65,518 publications. These additions bring our total number of non-redundant interactions to 1,232,786, raw interactions to 1,591,402, non-redundant chemical associations to 11,820, raw chemical associations to 27,785, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 19,047. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

BioGRID Version 3.4.162 Released

July 1, 2018 - 6:18 am

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 65,386 publications. These additions bring our total number of non-redundant interactions to 1,230,943, raw interactions to 1,588,606, non-redundant chemical associations to 11,820, raw chemical associations to 27,785, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 19,047. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

BioGRID Version 3.4.161 Released

June 1, 2018 - 3:18 am

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 65,218 publications. These additions bring our total number of non-redundant interactions to 1,228,924, raw interactions to 1,585,828, non-redundant chemical associations to 11,820, raw chemical associations to 27,785, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 19,047. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

BioGRID Version 3.4.160 Released

May 1, 2018 - 4:21 am

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 64,981 publications. These additions bring our total number of non-redundant interactions to 1,205,762, raw interactions to 1,553,656, non-redundant chemical associations to 11,820, raw chemical associations to 27,785, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 19,047. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

BioGRID Version 3.4.159 Released

April 1, 2018 - 3:36 am

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 64,826 publications. These additions bring our total number of non-redundant interactions to 1,202,227, raw interactions to 1,548,143, non-redundant chemical associations to 11,820, raw chemical associations to 27,785, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 19,047. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

National Institutes of HealthBiotechnology and Biological Sciences Research CouncilCanadian Institutes of Health ResearchThe University of EdinburghPrinceton UniversitySamuel Lunenfeld Research InstituteSaccharomyces Genome DatabaseFlybaseGeneDBNational Center for Biotechnology InformationHuman Protein Reference DatabaseWormbaseGene OntologyThe International Molecular Exchange ConsortiumDatabase of Interacting ProteinsIntACTMolecular Interaction DatabaseProteomics Standards InitiativeReactomeCytoscapeOsprey Network Visualization SystemPathway Commons