Saccharomyces cerevisiae (S288c)

SEC13

ANU3, GTPase-activating protein SEC13, L000001838, YLR208W
Structural component of 3 distinct complexes; subunit of Nup84 nuclear pore sub-complex (NPC), COPII vesicle coat, and Seh1-associated (SEA) complex; COPII vesicle coat is required for ER to Golgi transport; the Nup84 subcomplex contributes to nucleocytoplasmic transport, NPC biogenesis and processes that may require localization of chromosomes at the nuclear periphery, including transcription; homologous to human SEC13; abundance increases under DNA replication stress
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  • Interactors 313
  • Interactions 535
  • Network
  • PTM Sites 2