Saccharomyces cerevisiae (S288c)

PNC1

nicotinamidase, YGL037C
Nicotinamidase that converts nicotinamide to nicotinic acid; part of the NAD(+) salvage pathway; required for life span extension by calorie restriction; PNC1 expression responds to all known stimuli that extend replicative life span; protein increases in abundance and relative distribution to cytoplasmic foci decreases upon DNA replication stress
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33210
559292
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  • Interactors 118
  • Interactions 134
  • Network
  • PTM Sites 4