Saccharomyces cerevisiae (S288c)

PLC1

phosphatidylinositol phospholipase C, L000001448, YPL268W
Phospholipase C; hydrolyzes phosphatidylinositol 4,5-biphosphate (PIP2) to generate the signaling molecules inositol 1,4,5-triphosphate (IP3) and 1,2-diacylglycerol (DAG); involved in regulating many cellular processes; Plc1p and inositol polyphosphates are required for acetyl-CoA homeostasis which regulates global histone acetylation
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  • Interactors 105
  • Interactions 135
  • Network
  • PTM Sites 10